Lance-Leaf Coreopsis
Lance Leaf Coreopsis (Coreopsis lanceolata)
Lance-Leaf Coreopsis is an herbaceous perennial found in continental America and Eastern Asia, with C. lanceolata most commonly found in Korea (Kim et al., 2019). C. lanceolata is found to have antioxidant (Tanimoto et al., 2009), antiallergic (Shao et al., 2013), antibacterial (Shao et al., 2013), and antileukemic (Pardede et al., 2016) properties. One study indicates that C. lanceolata may have promise as a treatment against human colon cancer cells (Kim et al., 2019).
Latest Research
- The complete chloroplast genome of Coreopsis lanceolata L. and its phylogenetic analysis
by Chunfeng Wan on September 5, 2025 at 10:00 amCoreopsis lanceolata L. 1753 is a perennial herb of the family Asteraceae, often cultivated as an ornamental flower. The species has also been reported to contain a wide range of phytochemicals and to exhibit diverse pharmacological activities. To better understand the genetic information of C. lanceolata, its complete chloroplast genome was assembled and characterized for the first time in this study. The chloroplast genome was 150,448 bp long and contained 129 genes, including 86…
- Bacterial neuraminidase inhibitory chalcones from flowers of Coreopsis lanceolata, their kinetic characterization and antibiofilm effectby Seung Hwan Lee on June 2, 2024 at 10:00 am
CONCLUSION: The results showed that chalcones (1-8) and chalcone glucosides (9-12), metabolites isolated from the flowers of C. lanceolata, had BNA inhibitory and antibiofilm formation effect on E. coli.
- Lanceolanone A, a new biflavanone, and a chalcone glucoside from the flower heads of Coreopsis lanceolata and their aldose reductase inhibitory activity and AMPK activationby Yukiko Matsuo on September 6, 2022 at 10:00 am
The MeOH extract of the flower heads of Coreopsis lanceolata L. (Asteraceae) exhibited aldose reductase (AR) inhibitory activity (IC(50) 8.36 µg/mL). Bioassay-guided fractionation of the extract resulted in the isolation of a new biflavanone-named Lanceolanone A (1) and a chalcone glucoside (6), along with 12 known compounds (2-5 and 7-14), of which 4, 7, 9, 10, and 12 were isolated from C. lanceolata for the first time. The structures of the new compounds (1 and 6) were determined by extensive…
- Aurones and Flavonols from Coreopsis lanceolata L. Flowers and Their Anti-Oxidant, Pro-Inflammatory Inhibition Effects, and Recovery Effects on Alloxan-Induced Pancreatic Islets in Zebrafishby Hyoung-Geun Kim on October 23, 2021 at 10:00 am
(1) Background: Many flavonoids have been reported to exhibit pharmacological activity; a preparatory study confirmed that Coreopsis lanceolata flowers (CLFs) contained high flavonoid structure content; (2) Methods: CLFs were extracted in aqueous methanol (MeOH:H(2)O = 4:1) and fractionated into acetic ester (EtOAc), normal butanol (n-BuOH), and H(2)O fractions. Repeated column chromatographies for two fractions led to the isolation of two aurones and two flavonols; (3) Results: Four flavonoids…
- Anti-Neuroinflammatory and Anti-Inflammatory Activities of Phenylheptatriyne Isolated from the Flowers of Coreopsis lanceolata L. via NF-kappaB Inhibition and HO-1 Expression in BV2 and RAW264.7 Cellsby Hwan Lee on July 24, 2021 at 10:00 am
Aging is associated with immune disregulation and oxidative stress which lead to inflammation and neurodegenerative diseases. We have tried to identify the anti-neuroinflammatory and anti-inflammatory components of Coreopsis lanceolata L. The dried flowers of C. lanceolata were extracted with 70% EtOH, and the obtained extract was divided into CH(2)Cl(2), EtOAc, n-BuOH, and H(2)O fractions. The CH(2)Cl(2) fraction was separated using silica gel and C-18 column chromatography to yield…
References
Kim, H.-G., Oh, H.-J., Ko, J.-H., Song, H. S., Lee, Y.-G., Kang, S. C., Lee, D. Y., & Baek, N.-I. (2019). Lanceoleins A–G, hydroxychalcones, from the flowers of Coreopsis lanceolata and their chemopreventive effects against human colon cancer cells. Bioorganic Chemistry, 85, 274–281. https://doi.org/10.1016/j.bioorg.2019.01.003
Pardede, A., Mashita, K., Ninomiya, M., Tanaka, K., & Koketsu, M. (2016). Flavonoid profile and antileukemic activity of Coreopsis lanceolata flowers. Bioorganic and Medicinal Chemistry Letters, 26(12), 2784–2787. Scopus. https://doi.org/10.1016/j.bmcl.2016.04.069
Shao, D.-X., Zheng, D.-M., Hu, R., Chen, W., Chen, D.-M., & Zhuo, X.-Q. (2013). Chemical constituents from Coreopsis lanceolata and their bioactivities. Chinese Traditional and Herbal Drugs, 44(12), 1558–1561. Scopus. https://doi.org/10.7501/j.issn.0253-2670.2013.12.007
Tanimoto, S., Miyazawa, M., Inoue, T., Okada, Y., & Nomura, M. (2009). Chemical constituents of Coreopsis lanceolata L. and their physiological activities. Journal of Oleo Science, 58(3), 141–146. Scopus. https://doi.org/10.5650/jos.58.141